Which two organs are primarily affected in anaphylactic shock?

Anaphylactic shock is a severe and potentially life-threatening allergic reaction that occurs rapidly and can affect multiple organ systems. The two organs primarily impacted during this condition are the lungs and the cardiovascular system.

In anaphylaxis, the immune response leads to the release of histamine and other chemical mediators that cause widespread vasodilation and increased vascular permeability. This results in a sudden drop in blood pressure and can lead to inadequate blood flow to vital organs, affecting the cardiovascular system. The heart may also struggle to pump effectively due to this drop in blood pressure.

Simultaneously, the respiratory system is heavily involved as anaphylaxis can cause bronchoconstriction and bronchial edema, leading to wheezing, difficulty in breathing, and a potential airway obstruction. These respiratory symptoms are a direct result of the body’s inflammatory response to the allergen.

When addressing the other options, while the kidneys, liver, brain, and spinal cord can be affected due to secondary complications or as part of the body’s systemic response in a severe allergic reaction, the lungs and cardiovascular system are the primary organs directly involved in the acute phases of anaphylactic shock. Thus, focusing on the immediate life-threatening effects of the condition, the correct answer appropriately highlights the most